The idea of the knowability of the world is not the product of any simple faith, but the result of human intellectual efforts to dominate the public spiritual element, which has become helpless before Its Majesty — Rationalism.
The assumption that the human mind has limitations in understanding the ultimate questions of the universe due to the specifics of its evolutionary process is incorrect. Yes, the mind could form better, but it has led humans to the current level of development, while creating incredible sciences of cognition with a vast horizon for further improvement. Therefore, we are obliged to follow its rational conclusions.
Overall, science confirms the following assertions: humans aren't the only sentient entities in the Universe; the extinction of intelligent life is a natural, ordinary phenomenon; life on Earth might never have emerged and can vanish at any given moment. What's the conclusion? The Universe exists just because, without any inherent purpose. It is not designed for the emergence of intelligent beings. We are the result of a chaotic transformation of matter, and every day we advance in our understanding of the world and ourselves.
Which questions will remain unanswered by scientists? There are no questions that science will not eventually be able to comprehend and explain, it is only a matter of time. There may be certain details that are not crucial for understanding the overall picture of the world. For instance, perhaps, science may never give an exact answer to the question: How much time has passed before self-organizing matter appeared?, but since that period was the Era of Nothing, the concept of time loses its meaning, and therefore the answer to this question is not so important.
Why does the world exist? The universe exists simply without a cause. It either emerged spontaneously or has eternally existed — that's a separate topic. Inherently, it possesses a self-organizing property but lacks a predetermined purpose. The universe is essentially a specific possibility for the birth and formation of various complex phenomena, including primitive intelligent life. Over time, these phenomena either get destroyed or cease to exist, while new ones may emerge. However, intelligent beings have the opportunity to extend their existence if they manage to harness the potential of their inherent qualities and the capabilities of their surrounding world. Fortunately, the potential of fundamental human traits and the opportunities offered by the physical world for flourishing are extraordinary, and it is our choice whether we reach the stars or regress into dissolution.